Infrared Thermography as a Non-Invasive Tool to Explore Differences in the Musculoskeletal System of Children with Hemophilia Compared to an Age-Matched Healthy Group

Autor/in: Seuser, S.; K. Kurnik; A.-K. Mahlein
Jahr: 2018
Zeitschrift: Sensors
Seite/n: doi:10.3390/s18020518
Stichworte: hemophilia; infrared thermography; non-invasive; silent bleeds; hot-spot

Published in Projekt Veröffentlichungen, die keinem Projekt und keiner Abteilung zugeordnet sind / Abteilung Additional projects and publications

Abstract

Recurrent joint bleeds and silent bleeds are the most common clinical feature in patients with hemophilia. Every bleed causes an immediate inﬂammatory response and is the leading cause of chronic crippling arthropathy. With the help of infrared thermography we wanted to detect early differences between a group of clinical non-symptomatic children with hemophilia (CWH) with no history of clinically detected joint bleeds and a healthy age-matched group of children. This could help to discover early inﬂammation and help implement early treatment and preventative strategies. It could be demonstrated that infrared thermography is sensitive enough to detect more signs of early inﬂammatory response in the CWH than in healthy children. It seems to detect more side differences in temperature than clinical examination of silent symptoms detects tender points. Silent symptoms/tender points seem to be combined with early local inﬂammation. Using such a non-invasive and sensor-based early detection, prevention of overloading and bleeding might be achieved.

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